Protective Effect of Teprenone Against Acute Gastric Mucosal Lesions Induced by Compound 48/80, a Mast Cell Degranulator, in Rats

• Ngā kaituhi matua: Yoshiji Ohta (Author), Takashi Kobayashi (Author), Kazuo Inui (Author), Junji Yoshino (Author), Saburo Nakazawa (Author)
• Hōputu: Pukapuka
• I whakaputaina: Elsevier, 2003-01-01T00:00:00Z.
• Ngā marau: article
• Urunga tuihono: Connect to this object online.

ABSTRACT: The protective effect of teprenone, an anti-ulcer drug, against acute gastric mucosal lesions was examined in rats with a single intraperitoneal injection of compound 48/80 (0.75 mg/kg). Teprenone (50, 100, or 200 mg/kg) was orally administered 0.5 h before compound 48/80 treatment. Admini...