Carbamazepine Induces Platelet Apoptosis and Thrombocytopenia Through Protein Kinase A

• Main Authors: Weiling Xiao (Author), Kangxi Zhou (Author), Mengnan Yang (Author), Chenglin Sun (Author), Lan Dai (Author), Jian Gu (Author), Rong Yan (Author), Kesheng Dai (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Carbamazepine is extensively used worldwide to treat a wide range of disorders such as epilepsy, peripheral neuralgia and bipolar disorder. Thrombocytopenia and hemorrhage have been identified in multiple carbamazepine-treated patients. However, the underlying mechanism remains poorly understood. He...