Identification of both GABAA receptors and voltage-activated Na+ channels as molecular targets of anticonvulsant α-asarone

• Автори: Ze-Jun eWang (Автор), Simmon Rock Levinson (Автор), Liqin eSun (Автор), Thomas eHeinbockel (Автор)
• Формат: Книга
• Опубліковано: Frontiers Media S.A., 2014-03-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Alpha (α)-asarone, a major effective component isolated from the Chinese medicinal herb Acorus tatarinowii, is clinically used as medication for treating epilepsy, cough, bronchitis, and asthma. In the present study, we demonstrated that α-asarone targets central nervous system GABAA receptor as wel...