Canthin-6-One Inhibits Developmental and Tumour-Associated Angiogenesis in Zebrafish

• Main Authors: Mei Fong Ng (Author), Juliana Da Silva Viana (Author), Pei Jean Tan (Author), Denver D. Britto (Author), Sy Bing Choi (Author), Sakurako Kobayashi (Author), Norazwana Samat (Author), Dedrick Soon Seng Song (Author), Satoshi Ogawa (Author), Ishwar S. Parhar (Author), Jonathan W. Astin (Author), Benjamin M. Hogan (Author), Vyomesh Patel (Author), Kazuhide S. Okuda (Author)
• Format: Book
• Published: MDPI AG, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Tumour-associated angiogenesis play key roles in tumour growth and cancer metastasis. Consequently, several anti-angiogenic drugs such as sunitinib and axitinib have been approved for use as anti-cancer therapies. However, the majority of these drugs target the vascular endothelial growth factor A (...