Interleukin-27 Ameliorates Atherosclerosis in ApoE-/- Mice through Regulatory T Cell Augmentation and Dendritic Cell Tolerance

• Main Authors: Wenbin Xu (Author), Ruirui Zhu (Author), Zhengfeng Zhu (Author), Kunwu Yu (Author), Yue Wang (Author), Yan Ding (Author), Jian Yu (Author), Hongxia Tang (Author), Qiutang Zeng (Author), Yucheng Zhong (Author)
• Format: Book
• Published: Hindawi Limited, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Atherosclerosis, which is characterized by chronic inflammation in the arterial wall, is driven by immune cells and cytokines. Recent evidence indicated that interleukin (IL)-27 showed pleiotropic properties in immune diseases. However, precise mechanisms of IL-27, especially in atherosclerosis rema...