Spatio-temporal tracking and phylodynamics of an urban dengue 3 outbreak in São Paulo, Brazil.

• Main Authors: Adriano Mondini (Author), Roberta Vieira de Moraes Bronzoni (Author), Silvia Helena Pereira Nunes (Author), Francisco Chiaravalloti Neto (Author), Eduardo Massad (Author), Wladimir J Alonso (Author), Eduardo S M Lázzaro (Author), Amena Alcântara Ferraz (Author), Paolo Marinho de Andrade Zanotto (Author), Maurício Lacerda Nogueira (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2009-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The dengue virus has a single-stranded positive-sense RNA genome of approximately 10.700 nucleotides with a single open reading frame that encodes three structural (C, prM, and E) and seven nonstructural (NS1, NS2A, NS2B, NS3, NS4A, NS4B, and NS5) proteins. It possesses four antigenically distinct s...