Extract Enriched in Flavan-3-ols and Mainly Procyanidin Dimers Improves Metabolic Alterations in a Mouse Model of Obesity-Related Disorders Partially via Estrogen Receptor Alpha

• Main Authors: Daniela Leonetti (Author), Raffaella Soleti (Author), Nicolas Clere (Author), Luisa Vergori (Author), Caroline Jacques (Author), Lucie Duluc (Author), Catherine Dourguia (Author), Maria C. Martínez (Author), Ramaroson Andriantsitohaina (Author)
• פורמט: ספר
• יצא לאור: Frontiers Media S.A., 2018-04-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

Red wine polyphenol extracts improve cardiovascular and metabolic disorders linked to obesity. Their vascular protection is mediated by the activation of the alpha isoform of the estrogen receptor (ERα). In the present study, we explored the effects of a grape seed extract (GSE) enriched in the flav...