Protein target discovery of drug and its reactive intermediate metabolite by using proteomic strategy

Identifying protein targets of bioactive compounds is an effective approach to discover unknown protein functions, identify molecular mechanisms of drug action, and obtain information for optimization of lead compounds. At the same time, metabolic activation of a drug can lead to cytotoxicities. The...

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Bibliographic Details
Main Authors: Lianghai Hu (Author), John Paul Fawcett (Author), Jingkai Gu (Author)
Format: Book
Published: Elsevier, 2012-04-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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