Using toponomics to characterize phenotypic diversity in alveolar macrophages from male mice treated with exogenous SP-A1

• Автори: David S. Phelps (Автор), Vernon M. Chinchilli (Автор), Judith Weisz (Автор), Debra Shearer (Автор), Xuesheng Zhang (Автор), Joanna Floros (Автор)
• Формат: Книга
• Опубліковано: BMC, 2020-02-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Abstract Background We used the Toponome Imaging System (TIS) to identify "patterns of marker expression", referred to here as combinatorial molecular phenotypes (CMPs) in alveolar macrophages (AM) in response to the innate immune molecule, SP-A1. Methods We compared 114 AM from male SP-A...