GMP-compliant automated radiosynthesis of [18F] SynVesT-1 for PET imaging of synaptic vesicle glycoprotein 2 A (SV2A)

• Main Authors: Lijuan Chen (Author), Xiaochen Li (Author), Yao Ge (Author), Huiqiang Li (Author), Ruili Li (Author), Xiaosheng Song (Author), Jianfei Liang (Author), Weifeng Zhang (Author), Xiaona Li (Author), Xiaoqi Wang (Author), Yunjuan Wang (Author), Yaping Wu (Author), Yan Bai (Author), Meiyun Wang (Author)
• Format: Book
• Published: SpringerOpen, 2024-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background A novel positron emission tomography (PET) imaging tracer, [18F] SynVesT-1, targeting synaptic vesicle glycoprotein 2 (SV2A), has been developed to meet clinical demand. Utilizing the Trasis AllinOne-36 (AIO) module, we've automated synthesis to Good Manufacturing Practice (...