LncRNA ZNF593-AS alleviates diabetic cardiomyopathy via suppressing IRF3 signaling pathway

• Main Authors: Rong Xie (Author), Jiahui Fan (Author), Jianpei Wen (Author), Kunying Jin (Author), Jiabing Zhan (Author), Shuai Yuan (Author), Yuyan Tang (Author), Xiang Nie (Author), Zheng Wen (Author), Huaping Li (Author), Chen Chen (Author), Dao Wen Wang (Author)
• Format: Book
• Published: Elsevier, 2023-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Diabetes could directly induce cardiac injury, leading to cardiomyopathy. However, treatment strategies for diabetic cardiomyopathy remain limited. ZNF593-AS knockout and cardiomyocyte-specific transgenic mice were constructed. In addition, high-fat diet (HFD)-induced diabetic mouse model and db/db...