Daphnetin Alleviates Senile and Disuse Osteoporosis by Distinct Modulations of Bone Formation and Resorption

• Main Authors: Jing Gao (Author), Zhen Wang (Author), Peipei Gao (Author), Qiang Fan (Author), Tiantian Zhang (Author), Li Cui (Author), Liujia Shi (Author), Zhongbo Liu (Author), Zhiwei Yang (Author), Langchong He (Author), Chunyan Wang (Author), Yinghui Li (Author), Lina Qu (Author), Jiankang Liu (Author), Jiangang Long (Author)
• Format: Book
• Published: MDPI AG, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Senile and disuse osteoporosis have distinct bone turnover status and lack effective treatments. In this study, senescence-accelerated mouse prone 8 (SAMP8) and hindlimb unloading mouse models were used to explore the protective effects of daphnetin on these two types of osteoporosis, and primary os...