Calcium-Channel Antagonists Inhibit Marble-Burying Behavior in Mice

• Main Authors: Nobuaki Egashira (Author), Ryoko Okuno (Author), Moe Abe (Author), Michihiko Matsushita (Author), Kenichi Mishima (Author), Katsunori Iwasaki (Author), Ryozo Oishi (Author), Ryoji Nishimura (Author), Yoshiaki Matsumoto (Author), Michihiro Fujiwara (Author)
• Format: Book
• Published: Elsevier, 2008-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In the present study, we examined the effects of calcium-channel antagonists on marble-burying behavior, which is an animal model of obsessive-compulsive disorder. Amlodipine (10 mg/kg, i.p.), cilnidipine (10 mg/kg, i.p.), nilvadipine (3 and10 mg/kg, i.p.), and flunarizine (30 mg/kg, i.p.) significa...