Tocilizumab modifies clinical and laboratory features of macrophage activation syndrome complicating systemic juvenile idiopathic arthritis

• Main Authors: Masaki Shimizu (Author), Mao Mizuta (Author), Nami Okamoto (Author), Takahiro Yasumi (Author), Naomi Iwata (Author), Hiroaki Umebayashi (Author), Yuka Okura (Author), Noriko Kinjo (Author), Tomohiro Kubota (Author), Yasuo Nakagishi (Author), Kenichi Nishimura (Author), Mariko Mohri (Author), Masato Yashiro (Author), Junko Yasumura (Author), Hiroyuki Wakiguchi (Author), Masaaki Mori (Author)
• Format: Book
• Published: BMC, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background This study aimed to determine the influence of tocilizumab (TCZ) in modifying the clinical and laboratory features of macrophage activation syndrome (MAS) complicating systemic juvenile idiopathic arthritis (s-JIA). Furthermore, we assessed the performance of the 2016 MAS classif...