Mannose-functionalization of reconstituted high-density lipoprotein nanoparticles improves payload delivery and enhances M2-to-M1 phenotype reprogramming of RAW 264.7 macrophages polarized by B16-F10 melanoma cells

Mannose-functionalization of reconstituted high-density lipoprotein nanoparticles improves payload delivery and enhances M2-to-M1 phenotype reprogramming of RAW 264.7 macrophages polarized by B16-F10 melanoma cells

The targeting and conversion of the immunosuppressive (M2) tumor-associated macrophages (TAMs) to an immunostimulatory (M1) phenotype can induce tumor regression in advanced melanoma. We have previously characterized and reported the ability of reconstituted high-density lipoprotein nanoparticles (r...

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Main Authors: Akpedje S. Dossou (Author), Morgan E. Mantsch (Author), Nirupama Sabnis (Author), Rance E. Berg (Author), Rafal Fudala (Author), Andras G. Lacko (Author)
Format: Book
Published: Frontiers Media S.A., 2023-10-01T00:00:00Z.
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