Expression of Immunoglobulin Receptors with Distinctive Features Indicating Antigen Selection by Marginal Zone B Cells from Human Spleen

• Main Authors: Monica Colombo (Author), Giovanna Cutrona (Author), Daniele Reverberi (Author), Silvia Bruno (Author), Fabio Ghiotto (Author), Claudya Tenca (Author), Kostas Stamatopoulos (Author), Anastasia Hadzidimitriou (Author), Jenny Ceccarelli (Author), Sandra Salvi (Author), Simona Boccardo (Author), Maria Grazia Calevo (Author), Amleto De Santanna (Author), Mauro Truini (Author), Franco Fais (Author), Manlio Ferrarini (Author)
• Format: Book
• Published: BMC, 2013-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Marginal zone (MZ) B cells, identified as surface (s)IgMhighsIgDlowCD23low/−CD21+CD38− B cells, were purified from human spleens, and the features of their V(D)J gene rearrangements were investigated and compared with those of germinal center (GC), follicular mantle (FM) and switched memory...