Dose-dependent effect of daptomycin on the artificial prolongation of prothrombin time in coagulation abnormalities: in vitro verification

• Egile Nagusiak: Hideki Hashimoto (Egilea), Makoto Saito (Egilea), Naoki Kanda (Egilea), Takehito Yamamoto (Egilea), Makiko Mieno (Egilea), Shuji Hatakeyama (Egilea)
• Formatua: Liburua
• Argitaratua: BMC, 2017-11-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Abstract Background Several studies have reported that daptomycin induced artificial prolongation of prothrombin time (PT) in some test reagents, particularly in warfarin users. However, it remains unknown whether the artificial prolongation can be affected by coagulation abnormalities other than th...