Fast renal trapping of porcine Luteinizing Hormone (pLH) shown by ¹²³I-scintigraphic imaging in rats explains its short circulatory half-life

• Main Authors: Locatelli Alain (Author), Magallon Thierry (Author), Leroux Hervé (Author), Lecompte François (Author), Bernard Serge (Author), Klett Danièle (Author), Lepape Alain (Author), Combarnous Yves (Author)
• Format: Book
• Published: BMC, 2003-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Sugar moieties of gonadotropins play no primary role in receptor binding but they strongly affect their circulatory half-life and consequently their <it>in vivo </it>biopotencies. In order to relate more precisely hepatic...