Deletion of Six3 in post-proliferative neurons produces weakened SCN circadian output, improved metabolic function, and dwarfism in male mice

• Glavni autori: Jason D. Meadows (Autor), Joseph A. Breuer (Autor), Shanna N. Lavalle (Autor), Michael R. Hirschenberger (Autor), Meera M. Patel (Autor), Duong Nguyen (Autor), Alyssa Kim (Autor), Jessica Cassin (Autor), Michael R. Gorman (Autor), David K. Welsh (Autor), Pamela L. Mellon (Autor), Hanne M. Hoffmann (Autor)
• Format: Knjiga
• Izdano: Elsevier, 2022-03-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Objective: The increasing prevalence of obesity makes it important to increase the understanding of the maturation and function of the neuronal integrators and regulators of metabolic function. Methods: Behavioral, molecular, and physiological analyses of transgenic mice with Sine oculis 3 (Six3) de...