Blockade of Inflammation and Apoptosis Pathways by siRNA Prolongs Cold Preservation Time and Protects Donor Hearts in a Porcine Model

• मुख्य लेखकों: Jia Wei (लेखक), Shiyou Chen (लेखक), Song Xue (लेखक), Qiangru Zhu (लेखक), Sha Liu (लेखक), Li Cui (लेखक), Xiuguo Hua (लेखक), Yongyi Wang (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2017-12-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

In donor hearts from mini pigs, overtime cold preservation and ischemia-reperfusion injury cause poor graft quality and impaired heart function. Blockage of complement, apoptosis, and inflammation is considered a strategy for attenuating ischemia-reperfusion injury and protecting cardiac function. M...