Association between triglycerides, known risk SNVs and conserved rare variation in SLC25A40 in a multi-ancestry cohort

• मुख्य लेखकों: Elisabeth A. Rosenthal (लेखक), David R. Crosslin (लेखक), Adam S. Gordon (लेखक), David S. Carrell (लेखक), Ian B. Stanaway (लेखक), Eric B. Larson (लेखक), Jane Grafton (लेखक), Wei-Qi Wei (लेखक), Joshua C. Denny (लेखक), Qi-Ping Feng (लेखक), Amy S. Shah (लेखक), Amy C. Sturm (लेखक), Marylyn D. Ritchie (लेखक), Jennifer A. Pacheco (लेखक), Hakon Hakonarson (लेखक), Laura J. Rasmussen-Torvik (लेखक), John J. Connolly (लेखक), Xiao Fan (लेखक), Maya Safarova (लेखक), Iftikhar J. Kullo (लेखक), Gail P. Jarvik (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: BMC, 2021-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Abstract Background Elevated triglycerides (TG) are associated with, and may be causal for, cardiovascular disease (CVD), and co-morbidities such as type II diabetes and metabolic syndrome. Pathogenic variants in APOA5 and APOC3 as well as risk SNVs in other genes [APOE (rs429358, rs7412), APOA1/C3/...