Association between triglycerides, known risk SNVs and conserved rare variation in SLC25A40 in a multi-ancestry cohort

Abstract Background Elevated triglycerides (TG) are associated with, and may be causal for, cardiovascular disease (CVD), and co-morbidities such as type II diabetes and metabolic syndrome. Pathogenic variants in APOA5 and APOC3 as well as risk SNVs in other genes [APOE (rs429358, rs7412), APOA1/C3/...

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Main Authors: Elisabeth A. Rosenthal (Author), David R. Crosslin (Author), Adam S. Gordon (Author), David S. Carrell (Author), Ian B. Stanaway (Author), Eric B. Larson (Author), Jane Grafton (Author), Wei-Qi Wei (Author), Joshua C. Denny (Author), Qi-Ping Feng (Author), Amy S. Shah (Author), Amy C. Sturm (Author), Marylyn D. Ritchie (Author), Jennifer A. Pacheco (Author), Hakon Hakonarson (Author), Laura J. Rasmussen-Torvik (Author), John J. Connolly (Author), Xiao Fan (Author), Maya Safarova (Author), Iftikhar J. Kullo (Author), Gail P. Jarvik (Author)
Format: Book
Published: BMC, 2021-01-01T00:00:00Z.
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3rd Floor Main Library

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