Association between triglycerides, known risk SNVs and conserved rare variation in SLC25A40 in a multi-ancestry cohort

• Váldodahkkit: Elisabeth A. Rosenthal (Dahkki), David R. Crosslin (Dahkki), Adam S. Gordon (Dahkki), David S. Carrell (Dahkki), Ian B. Stanaway (Dahkki), Eric B. Larson (Dahkki), Jane Grafton (Dahkki), Wei-Qi Wei (Dahkki), Joshua C. Denny (Dahkki), Qi-Ping Feng (Dahkki), Amy S. Shah (Dahkki), Amy C. Sturm (Dahkki), Marylyn D. Ritchie (Dahkki), Jennifer A. Pacheco (Dahkki), Hakon Hakonarson (Dahkki), Laura J. Rasmussen-Torvik (Dahkki), John J. Connolly (Dahkki), Xiao Fan (Dahkki), Maya Safarova (Dahkki), Iftikhar J. Kullo (Dahkki), Gail P. Jarvik (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: BMC, 2021-01-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Abstract Background Elevated triglycerides (TG) are associated with, and may be causal for, cardiovascular disease (CVD), and co-morbidities such as type II diabetes and metabolic syndrome. Pathogenic variants in APOA5 and APOC3 as well as risk SNVs in other genes [APOE (rs429358, rs7412), APOA1/C3/...