Preparation, characterization and pharmacokinetics of Cucurbitacin B solid dispersion

• Main Authors: Qian Wu (Author), Ziting Huang (Author), Ya Xiao (Author), Jinhua Chang (Author), Pei Liu (Author), Cuizhe Liu (Author), Xigang Liu (Author)
• Format: Book
• Published: Elsevier, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cucurbitacin B (CuB) is a type of tetracyclic triterpenoids derived from the Cucurbitaceae melon, which has various biological activities. However, the poor water solubility and low bioavailability of CuB limit its wide range of clinical applications. Objective: The present study aimed at the prepar...