The Role of Nrf2 in the PM-Induced Vascular Injury Under Real Ambient Particulate Matter Exposure in C57/B6 Mice

• Main Authors: Mengyu Gao (Author), Yuanyuan Ma (Author), Jing Luo (Author), Daochuan Li (Author), Menghui Jiang (Author), Qixiao Jiang (Author), Jingbo Pi (Author), Rui Chen (Author), Wen Chen (Author), Rong Zhang (Author), Yuxin Zheng (Author), Lianhua Cui (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Short-and long-term exposure to particulate matter (PM) has been associated with cardiovascular disease (CVD). It is well recognized that oxidative stress is a potential major mechanism in PM-induced vascular injuries, in which the nuclear factor E2-related factor 2 (Nrf2) signaling pathway plays a...