Intestinal Transcytosis of a Protein Cargo and Nanoparticles Mediated by a Non-Toxic Form of <i>Pseudomonas aeruginosa</i> Exotoxin A

• Main Authors: Ruiying Li (Author), Floriane Laurent (Author), Alistair Taverner (Author), Julia Mackay (Author), Paul A. De Bank (Author), Randall J. Mrsny (Author)
• Format: Book
• Published: MDPI AG, 2021-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The low permeability of nanoparticles (NPs) across the intestinal epithelium remains a major challenge for their application of delivering macromolecular therapeutic agents via the oral route. Previous studies have demonstrated the epithelial transcytosis capacity of a non-toxic version of <i>...