Population Pharmacokinetics and Model-Based Dosing Optimization of Teicoplanin in Pediatric Patients

• Glavni autori: Tao Zhang (Autor), Dan Sun (Autor), Zuocheng Shu (Autor), Ziyun Duan (Autor), Yang Liu (Autor), Qian Du (Autor), Ying Zhang (Autor), Yuzhu Dong (Autor), Taotao Wang (Autor), Sasa Hu (Autor), Hua Cheng (Autor), Yalin Dong (Autor)
• Format: Knjiga
• Izdano: Frontiers Media S.A., 2020-12-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Objectives: The pharmacokinetics (PK) of teicoplanin differs in children compared with adults. Our aim was to determine the PK of teicoplanin in an Asian pediatric population and to optimize dosage regimens.Methods: This was a retrospective PK study and all the data were collected from hospitalized...