New Derivatives of the Multi-Stage Active Malaria Box Compound MMV030666 and Their Antiplasmodial Potencies

• Main Authors: Theresa Hermann (Author), Robin Wallner (Author), Johanna Dolensky (Author), Werner Seebacher (Author), Eva-Maria Pf (Author), Marcel Kaiser (Author), Pascal Mäser (Author), Robert Weis (Author)
• Format: Book
• Published: MDPI AG, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

MMV's Malaria Box compound MMV030666 shows multi-stage activity against various strains of <i>Plasmodium falciparum</i> and lacks resistance development. To evaluate the importance of its diarylether partial structure, diarylthioethers and diphenylamines with varying substitution pa...