Polydopamine and peptide decorated doxorubicin-loaded mesoporous silica nanoparticles as a targeted drug delivery system for bladder cancer therapy

• Hlavní autoři: Yi Wei (Autor), Li Gao (Autor), Lu Wang (Autor), Lin Shi (Autor), Erdong Wei (Autor), Baotong Zhou (Autor), Li Zhou (Autor), Bo Ge (Autor)
• Médium: Kniha
• Vydáno: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

We reported a simple polydopamine (PDA)-based surface modification method to prepare novel targeted doxorubicin-loaded mesoporous silica nanoparticles and peptide CSNRDARRC conjugation (DOX-loaded MSNs@PDA-PEP) for enhancing the therapeutic effects on bladder cancer. Drug-loaded NPs were characteriz...