Development and Evaluation of Novel Leflunomide SPION Bioemulsomes for the Intra-Articular Treatment of Arthritis

• Main Authors: Haidy Abbas (Author), Heba A. Gad (Author), Nesrine S El Sayed (Author), Laila Ahmed Rashed (Author), Mohamed A. Khattab (Author), Ahmad O. Noor (Author), Mariam Zewail (Author)
• Format: Book
• Published: MDPI AG, 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Systemic treatments for rheumatoid arthritis are associated with many side effects. This study aimed to minimize the side effects associated with the systemic administration of leflunomide (LEF) by formulating LEF-loaded emulsomes (EMLs) for intra-articular administration. Additionally, EMLs were lo...