High prevalence of Arginine to Glutamine Substitution at 98, 141 and 162 positions in Troponin I (<it>TNNI3</it>) associated with hypertrophic cardiomyopathy among Indians

High prevalence of Arginine to Glutamine Substitution at 98, 141 and 162 positions in Troponin I (<it>TNNI3</it>) associated with hypertrophic cardiomyopathy among Indians

<p>Abstract</p> <p>Background</p> <p>Troponin I (<it>TNNI3</it>) is the inhibitory subunit of the thin filament regulatory complex Troponin, which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. Mutations (2-7%) in this gene had be...

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Main Authors: Rani Deepa (Author), Nallari Pratibha (Author), Priyamvada Singh (Author), Narasimhan Calambur (Author), Singh Lalji (Author), Thangaraj Kumarasamy (Author)
Format: Book
Published: BMC, 2012-08-01T00:00:00Z.
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