Inhalation of an RNA aptamer that selectively binds extracellular histones protects from acute lung injury

• Príomhchruthaitheoirí: Beilei Lei (Údar), Chaojian Wang (Údar), Kamie Snow (Údar), Murilo E. Graton (Údar), Robert M. Tighe (Údar), Ammon M. Fager (Údar), Maureane R. Hoffman (Údar), Paloma H. Giangrande (Údar), Francis J. Miller, Jr (Údar)
• Formáid: LEABHAR
• Foilsithe / Cruthaithe: Elsevier, 2023-03-01T00:00:00Z.
• Ábhair: article
• Rochtain ar líne: Connect to this object online.

Acute lung injury (ALI) is a syndrome of acute inflammation, barrier disruption, and hypoxemic respiratory failure associated with high morbidity and mortality. Diverse conditions lead to ALI, including inhalation of toxic substances, aspiration of gastric contents, infection, and trauma. A shared m...