Therapeutic Drug Monitoring of Ceftazidime-Avibactam Concentrations in Carbapenem-Resistant K. pneumoniae-Infected Patients With Different Kidney Statuses

• Main Authors: Xin-Qi Teng (Author), Qiang Qu (Author), Yue Luo (Author), Wen-Ming Long (Author), Hai-Hui Zhuang (Author), Jiao-Hua Xu (Author), Yu-Xin Wen (Author), Hui-Lin Zhang (Author), Jian Qu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aims: Carbapenem-resistant K. pneumoniae (CRKP) is the most common carbapenem-resistant Enterobacteriaceae with high mortality. Ceftazidime-avibactam (CAZ-AVI) has exhibited excellent in vitro activity in vivo against CRKP. However, the efficacy of CAZ-AVI in KPC-producing CRKP-infected patients wit...