The Protective Effect of Lidocaine on Septic Rats via the Inhibition of High Mobility Group Box 1 Expression and NF-κB Activation

Lidocaine, a common local anesthetic drug, has anti-inflammatory effects. It has demonstrated a protective effect in mice from septic peritonitis. However, it is unknown whether lidocaine has effects on high mobility group box 1 (HMGB1), a key mediator of inflammation. In this study, we investigated...

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Main Authors: Huan-Liang Wang (Author), Yan-Qiu Xing (Author), Ying-Xue Xu (Author), Fei Rong (Author), Wei-Fu Lei (Author), Wen-Hua Zhang (Author)
Format: Book
Published: Hindawi Limited, 2013-01-01T00:00:00Z.
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3rd Floor Main Library

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