Optimization and validation of RP-HPLC method for evaluation of pyrrole -containing hydrazones in isolated rat synaptosomes
In the current study, RP-HPLC method for evaluation of 2 pyrrol-based hydrazones in isolated rat synaptosomes was optimized and validated according to ICH guidelines. The synaptosomes were obtained by multiple centrifugations with Percoll reagent and the selected 2 N-pyrollyl hydrazide-hydrazones we...
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| Format: | Livre |
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Pensoft Publishers,
2023-10-01T00:00:00Z.
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A1234.567 |
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