Formulation and Evaluation of Eudragit RL-100 Nanoparticles Loaded In-Situ Forming Gel for Intranasal Delivery of Rivastigmine

• Main Authors: Sara Salatin (Author), Jaleh Barar (Author), Mohammad Barzegar-Jalali (Author), Khosro Adibkia (Author), Mitra Alami-Milani (Author), Mitra Jelvehgari (Author)
• Format: Book
• Published: Tabriz University of Medical Sciences, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose: Rivastigmine hydrogen tartrate (RHT) is commonly used for the treatment of mild to moderate Alzheimer's disease (AD). The aim of this work was to formulate in-situ pluronic F-127 (PF-127) hydrogels containing Eudragit RL-100 (EU-RL) nanoparticles (NPs) in order to improve the therapeut...