Adenovirus vectored IFN-α protects mice from lethal challenge of Chikungunya virus infection.

• Main Authors: Huixin Chen (Author), Nyo Min (Author), Luyao Ma (Author), Chee-Keng Mok (Author), Justin Jang Hann Chu (Author)
• 格式: 图书
• 出版: Public Library of Science (PLoS), 2020-12-01T00:00:00Z.
• 主题: article
• 在线阅读: Connect to this object online.

Chikungunya virus (CHIKV) is a mosquito-borne pathogen that is responsible for numerous large and geographical epidemics, causing millions of cases. However, there is no vaccine or therapeutics against CHIKV infection available. Interferon-alpha (IFN-α) has been shown to produce potent antiviral res...