Enhanced anti-angiogenetic effect of transferrin receptor-mediated delivery of VEGF-trap in a glioblastoma mouse model

• Главные авторы: Peng Zhao (Автор), Yasuaki Anami (Автор), Peng Gao (Автор), Xuejun Fan (Автор), Leike Li (Автор), Kyoji Tsuchikama (Автор), Ningyan Zhang (Автор), Zhiqiang an (Автор)
• Формат: ‌
• Опубликовано: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Предметы: article
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Glioblastoma (GBM) is a common and aggressive brain cancer that accounts for 60% of adult brain tumors. Anti-angiogenesis therapy is an attractive option due to the high vasculature density of GBM. However, the best-known anti-angiogenic therapeutics, bevacizumab, and aflibercept, have failed to sho...