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Delivery of germacrone (GER) using macrophages-targeted polymeric nanoparticles and its application in rheumatoid arthritis

Macrophages can transform into M1 (pro-inflammatory) and M2 (anti-inflammatory) phenotypes, which mediate the immune/inflammatory response in rheumatoid arthritis (RA). Activated M1 phenotype macrophages and overexpression of folate (FA) receptors are abundant in inflammatory synovium and joints and...

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Main Authors: Tingfei Tan (Author), Qi Huang (Author), Weiwei Chu (Author), Bo Li (Author), Jingjing Wu (Author), Quan Xia (Author), Xi Cao (Author)
Format: Book
Published: Taylor & Francis Group, 2022-12-01T00:00:00Z.
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