Biological exploration of a novel 1,2,4-triazole-indole hybrid molecule as antifungal agent

• Główni autorzy: Fabrice Pagniez (Autor), Nicolas Lebouvier (Autor), Young Min Na (Autor), Isabelle Ourliac-Garnier (Autor), Carine Picot (Autor), Marc Le Borgne (Autor), Patrice Le Pape (Autor)
• Format: Książka
• Wydane: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

(2-(2,4-Dichlorophenyl)-3-(1H-indol-1-yl)-1-(1,2,4-1H-triazol-1-yl)propan-2-ol (8 g), a new 1,2,4-triazole-indole hybrid molecule, showed a broad-spectrum activity against Candida, particularly against low fluconazole-susceptible species. Its activity was higher than fluconazole and similar to voric...