Herb-drug interaction: Effect of sinapic acid on the pharmacokinetics of dasatinib in rats

• Main Authors: Mudassar Shahid (Author), Ajaz Ahmad (Author), Mohammad Raish (Author), Yousef A Bin Jardan (Author), Khalid M. Alkharfy (Author), Abdul Ahad (Author), Mohd Abul Kalam (Author), Mushtaq Ahmad Ansari (Author), Muzaffer Iqbal (Author), Naushad Ali (Author), Fahad I. Al-Jenoobi (Author)
• Format: Book
• Published: Elsevier, 2023-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Dasatinib (DAS) is a narrow therapeutic index drug and novel oral multitarget inhibitor of tyrosine kinase and approved for the first-line therapy for chronic myelogenous leukemia (CML) and Philadelphia chromosome (Ph + ) acute lymphoblastic leukemia (ALL). DAS, a known potent substrate of cytochrom...