Demethylation of H3K9 and H3K27 Contributes to the Tubular Renal Damage Triggered by Endoplasmic Reticulum Stress

• Үндсэн зохиолчид: Paula Diaz-Bulnes (Зохиогч), Maria Laura Saiz (Зохиогч), Viviana Corte-Iglesias (Зохиогч), Raúl R Rodrigues-Diez (Зохиогч), Aida Bernardo Florez (Зохиогч), Cristian Ruiz Bernet (Зохиогч), Cristina Martin Martin (Зохиогч), Marta Ruiz-Ortega (Зохиогч), Beatriz Suarez-Alvarez (Зохиогч), Carlos López-Larrea (Зохиогч)
• Формат: Ном
• Хэвлэсэн: MDPI AG, 2022-07-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Loss of protein homeostasis (proteostasis) in the endoplasmic reticulum (ER) activates the unfolded protein response (UPR), restoring correct protein folding. Sustained ER stress exacerbates activation of the major UPR branches (IRE1α/XBP1, PERK/ATF4, ATF6), inducing expression of numerous genes inv...