Angiogenesis is Inhibited by Arsenic Trioxide Through Downregulation of the CircHIPK3/miR-149-5p/FOXO1/VEGF Functional Module in Rheumatoid Arthritis

• Үндсэн зохиолчид: Juan Zhang (Зохиогч), Yeye Ma (Зохиогч), Yue Zhang (Зохиогч), Sijia Niu (Зохиогч), Maolin Chu (Зохиогч), Zhiyi Zhang (Зохиогч)
• Формат: Ном
• Хэвлэсэн: Frontiers Media S.A., 2021-10-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Angiogenesis is a crucial event in the pathogenesis of rheumatoid arthritis (RA). Arsenic trioxide (ATO, As2O3) has been reported to inhibit synovial angiogenesis via the vascular endothelial growth factor (VEGF)-centered functional module. However, the exact mechanisms of ATO on VEGF modulation rem...