Ugonin J Acts as a SARS-CoV-2 3C-like Protease Inhibitor and Exhibits Anti-inflammatory Properties

• Main Authors: Wei-Chung Chiou (Author), Hsu-Feng Lu (Author), Nung-Yu Hsu (Author), Tein-Yao Chang (Author), Yuan-Fan Chin (Author), Ping-Cheng Liu (Author), Jir-Mehng Lo (Author), Yeh B Wu (Author), Jinn-Moon Yang (Author), Cheng Huang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection causes severe "flu-like" symptoms that can progress to acute respiratory distress syndrome (ARDS), pneumonia, renal failure, and death. From the therapeutic perspective, 3-chymotrypsin-like protein (3CLpro) is a plausib...