Rapamycin Induces Autophagy and Reduces the Apoptosis of Podocytes Under a Stimulated Condition of Immunoglobulin A Nephropathy

• Main Authors: Shikai Liang (Author), Juan Jin (Author), Bo Lin (Author), Jianguang Gong (Author), Yiwen Li (Author), Qiang He (Author)
• Format: Book
• Published: Karger Publishers, 2017-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Backgroud/Aims: The aim of this study was to investigate the potential renoprotective effect of rapamycin on the autophagy of podocytes treated with the supernatant of mesangial cells cultured with aggregated IgA1 (aIgA1) from immunoglobulin A nephropathy (IgAN) patients. Methods: Monomeric IgA1 (mI...