Early and late endothelial response in breast cancer metastasis in mice: simultaneous quantification of endothelial biomarkers using a mass spectrometry-based method

• Main Authors: Joanna Suraj (Author), Anna Kurpińska (Author), Agnieszka Zakrzewska (Author), Magdalena Sternak (Author), Marta Stojak (Author), Agnieszka Jasztal (Author), Maria Walczak (Author), Stefan Chlopicki (Author)
• Format: Book
• Published: The Company of Biologists, 2019-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The endothelium plays an important role in cancer metastasis, but the mechanisms involved are still not clear. In the present work, we characterised the changes in endothelial function at early and late stages of breast cancer progression in an orthotopic model of murine mammary carcinoma (4T1 cells...