RNA Profiling Reveals a Common Mechanism of Histone Gene Downregulation and Complementary Effects for Radioprotectants in Response to Ionizing Radiation

• Main Authors: Changhui Ge (Author), Fei Su (Author), Hanjiang Fu (Author), Yuan Wang (Author), Baolei Tian (Author), Bin Liu (Author), Jie Zhu (Author), Yong Ding (Author), Xiaofei Zheng (Author)
• Format: Book
• Published: SAGE Publishing, 2020-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

High-dose ionizing radiation (IR) alters the expression levels of non-coding RNAs (ncRNAs). However, the roles of ncRNAs and mRNAs in mediating radiation protection by radioprotectants remain unknown. Microarrays were used to determine microRNA (miRNA), long ncRNA (lncRNA), and mRNA expression profi...