Recipient rs1045642 Polymorphism Is Associated With Office Blood Pressure at 1-Year Post Kidney Transplantation: A Single Center Pharmacogenetic Cohort Pilot Study

• Main Authors: Yassine Bouatou (Author), Ludwig Stenz (Author), Belen Ponte (Author), Serge Ferrari (Author), Ariane Paoloni-Giacobino (Author), Karine Hadaya (Author)
• Formato: Libro
• Publicado: Frontiers Media S.A., 2018-03-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

Background: Corticosteroids are associated with reduced bone mineral density (BMD), as well as water and salt retention, leading to hypertension. They are substrates for P-glycoprotein, a protein coded by the highly polymorphic ABCB1 gene. We hypothesized that one ABCB1 polymorphism, rs1045642, is a...