Deciphering the therapeutic potential of trimetazidine in rheumatoid arthritis via targeting mi-RNA128a, TLR4 signaling pathway, and adenosine-induced FADD-microvesicular shedding: In vivo and in silico study

• Main Authors: Enas Omran (Author), Abdullah R. Alzahrani (Author), Samar F. Ezzat (Author), Ghada Ellithy (Author), Marwa Tarek (Author), Eman Khairy (Author), Mohamed M. Ghit (Author), Ahmed Elgeushy (Author), Tahani Mohamed Ibrahim Al-Hazani (Author), Ibrahim Abdel Aziz Ibrahim (Author), Alaa Hisham Falemban (Author), Ghazi A. Bamagous (Author), Nasser A. Elhawary (Author), Mariusz Jaremko (Author), Essa M. Saied (Author), Doaa I. Mohamed (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Rheumatoid arthritis (RA) is a debilitating autoimmune condition characterized by chronic synovitis, joint damage, and inflammation, leading to impaired joint functionality. Existing RA treatments, although effective to some extent, are not without side effects, prompting a search for more potent th...