Novel mutation of the NOTCH3 gene in Arabic family with CADASIL

• Hoofdauteur: Saeed Bohlega (Auteur)
• Formaat: Boek
• Gepubliceerd in: MDPI AG, 2011-07-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Mutations in the NOTCH3 gene are responsible for cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), an adult onset hereditary angiopathy leading to ischemic stroke, vascular dementia and psychiatric disorders. All mutation of NOTCH3 described so far...