Curcumenol Mitigates the Inflammation and Ameliorates the Catabolism Status of the Intervertebral Discs In Vivo and In Vitro via Inhibiting the TNFα/NFκB Pathway

Curcumenol Mitigates the Inflammation and Ameliorates the Catabolism Status of the Intervertebral Discs In Vivo and In Vitro via Inhibiting the TNFα/NFκB Pathway

Low back pain (LBP) caused by intervertebral disc degeneration (IVDD) is accredited to the release of inflammatory cytokines followed by biomechanical and structural deterioration. In our study, we used a plant-derived medicine, curcumenol, to treat IVDD. A cell viability test was carried out to eva...

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Main Authors: Xiao Yang (Author), Baixing Li (Author), Haijun Tian (Author), Xiaofei Cheng (Author), Tangjun Zhou (Author), Jie Zhao (Author)
Format: Book
Published: Frontiers Media S.A., 2022-06-01T00:00:00Z.
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