Endothelial Iron Homeostasis Regulates Blood-Brain Barrier Integrity via the HIF2α-Ve-Cadherin Pathway

• Главные авторы: Daniel Rand (Автор), Orly Ravid (Автор), Dana Atrakchi (Автор), Hila Israelov (Автор), Yael Bresler (Автор), Chen Shemesh (Автор), Liora Omesi (Автор), Sigal Liraz-Zaltsman (Автор), Fabien Gosselet (Автор), Taber S. Maskrey (Автор), Michal Schnaider Beeri (Автор), Peter Wipf (Автор), Itzik Cooper (Автор)
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• Опубликовано: MDPI AG, 2021-02-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

The objective of this study was to investigate the molecular response to damage at the blood-brain barrier (BBB) and to elucidate critical pathways that might lead to effective treatment in central nervous system (CNS) pathologies in which the BBB is compromised. We have used a human, stem-cell deri...