Endothelial Iron Homeostasis Regulates Blood-Brain Barrier Integrity via the HIF2α-Ve-Cadherin Pathway

• 主要な著者: Daniel Rand (著者), Orly Ravid (著者), Dana Atrakchi (著者), Hila Israelov (著者), Yael Bresler (著者), Chen Shemesh (著者), Liora Omesi (著者), Sigal Liraz-Zaltsman (著者), Fabien Gosselet (著者), Taber S. Maskrey (著者), Michal Schnaider Beeri (著者), Peter Wipf (著者), Itzik Cooper (著者)
• フォーマット: 図書
• 出版事項: MDPI AG, 2021-02-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

The objective of this study was to investigate the molecular response to damage at the blood-brain barrier (BBB) and to elucidate critical pathways that might lead to effective treatment in central nervous system (CNS) pathologies in which the BBB is compromised. We have used a human, stem-cell deri...